Silicone Contamination in Lucentis Injections

We have previously written about re-packaged Avastin injections becoming contaminated with silicone oil. Injections of Lucentis may also carry this same risk of silicone contamination.

  • Lucentis (generic name: ranibizumab) is manufactured by Genentech, Inc. (which also manufactures Avastin).

Lucentis are prescription medications used to treat various forms of macular degeneration. They can also treat diabetic macular edema, diabetic retinopathy, and myopic choroidal neovascularization. Like Avastin, and Lucentis are anti-VEGF (anti-vascular endothelial growth factor) medications. VEGF is a protein that is one of the causes of leaky blood vessels in the eye. Elyea and Lucentis are thought to work by blocking this protein, hence the name “anti-VEGF” medications.

Elyea and Lucentis are administered by an injection into the eye. To be injected into the eye, Elyea and Lucentis must first be placed into a syringe. Both Elyea and Lucentis are delivered to the doctor in small vials and the solution must be drawn out using a syringe (see picture). The needle is then replaced with a smaller needle for injection into the eye.

Lucentis is also now available in a pre-filled syringe (seen in picture).

Silicone is used to lubricate the barrel of many syringes. As we have previously reported (here), silicone from the syringe can leach into the solution, which results in silicone droplets / particles being injected into the patient’s eye. If this occurs, the silicone particles can obstruct a person’s vision and severely interfere with daily life.

If you have experienced silicone oil or silicone particles being injected into your eye during an injection of Lucentis, or Avastin, please do not hesitate to contact one of our experienced attorneys at Spangenberg Shibley & Liber. We are actively investigating cases involving silicone contaminated eye injections from various product manufacturers, and we would be happy to review your case personally and discuss with you whether you have a valid claim for compensation. Consultations are free and confidential. Call (216) 600-0114 to request yours.

Diagram of How to Fill Syringe With Liquid

Diagram of the Parts of a Syringe: Cap, Rubber Stopper, Finger Grip, Luer Lock, Dose Mark, and Plunger Rod


    I was having a hard time finding someone to represent me. I was frustrated. But after SS&L took my case, I was treated VERY well! Ericka Campbell is a rockstar! She was phenomenal at communicating with me. Spangenberg Shibley & Liber are the utmost

    - William R.

    SS&L treated me well and I felt supported.

    - Brian R.

    Our Family will be Forever Grateful!

    - Tim S.

    Attorney Tor and the whole team at Spangenberg Shibley & Liber, including the receptionist, made me feel welcome, comforted, and confident throughout my case. They showed me respect and kindness from start to finish.

    - Zandra S.

    I was feeling uncertain but after I met with Nick I felt at ease & confident. Communication was great, I was constantly informed and everyone was genuine & compassionate.

    - Sonja S.

Put Award-Winning
Trial Lawyers On Your Side

Contact Our Team for a Free & Confidential Case Evaluation
  • Please enter your first name.
  • Please enter your last name.
  • Please enter your phone number.
    This isn't a valid phone number.
  • Please enter your email address.
    This isn't a valid email address.
  • Please make a selection.
  • Please enter a message.